Figure 3 - full size

 

Figure 3.
Fig. 3. Superposition of binding pockets of the wild type (yellow) and mutant (gray) structures. The estradiol A ring superposes perfectly in both structures, whereas the D-ring is slightly shifted.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2001, 276, 15059-15065) copyright 2001.