Figure 3 - full size

 

Figure 3.
Figure 3. Loop ordering on NO binding. Space filling views of the distal pockets in the NP4 -NO (left) and NP4 -CN- (right) structures. The view is from above the distal pocket, with heme shown in black, heme oxygens in orange, NO in magenta, CN- in cyan, five water molecules in red, and loops A-B and G-H in green. Binding of NO leads to reordering of the A-B and G-H loops, expulsion of the water molecules, burying of NO and Asp 30, and packing of Leu 130 against the NO molecule.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (2000, 7, 551-554) copyright 2000.