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Figure 3.
Figure 3 Stereoview of the SGAP active site. The refined new
structure of the native enzyme at 1.58 Å (blue) is superimposed
on the old structure of the native enzyme at 1.75 Å (green). It
is demonstrated that most of the active site is identical,
except for the non-protein ligand of the active-site zinc ions
[a phosphate ion (PO4) for the old structure and a water
molecule (WAT) for the new structure] observed approximately in
the same coordination site between the two metal ions (Zn1 and
Zn2). The difference in this zinc ligand is probably the main
factor causing positional differences for the active-site water
molecules between the old (green) and the new (blue) structures.
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