Figure 3 - full size

 

Figure 3.
Figure 3. The molecular interface of the Im3 dimer. Monomers A and B are depicted as Ca traces. Residues at the interface are shown in ball-and-stick representation in green (monomer A) and blue (monomer B). A major intermolecular interaction is the covalent cross-link of the thiols via a zinc ion, shown in yellow. Additional interactions include two intermolecular hydrogen bonds as well as hydrophobic interactions involving the nonpolar atoms of nine residues from monomer A, and seven residues from monomer B (see text). Furthermore, there are two water molecules, shown in red, that mediate the interaction between the monomers. (This figure was made with the program MOLSCRIPT [43].)

The above figure is reprinted by permission from Cell Press: Structure (1999, 7, 1365-1372) copyright 1999.