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Figure 4.
Figure 4. Similarity of Topology to Restriction Type II
Endonucleases(A–C) Ribbon diagrams of (A) Vsr, (B) one subunit
of BamHI ([32]), and (C) one subunit of EcoRV ( [46]) after
superimposition of the side chain of the first conserved
aspartate in the conserved catalytic motif and overlaying β
strands. Figures were derived from 1bhm and 1rvb. Side chains
important for endonuclease activity are depicted. Carbon,
oxygen, and nitrogen atoms are depicted in green, red, and blue,
respectively.(D) Enlarged view of superimposed Vsr (blue), BamHI
(brown), and EcoRV (green) active sites, with side chains from
the active site motif displayed.
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