Figure 2.
Figure 2. The substrate fragments. The natural substrate of
TS, dUMP (1), can be subdivided into several fragments, of which
various combinations are commercially available. These include
2'-deoxyuridine (dUrd; 2), 2'5'-dideoxyuridine (ddUrd; 3),
uridine (Urd; 4), phosphoribose (PR; 5), and phosphate
(PO[4]^2-; 6).
The above figure is reprinted
by permission from Cell Press:
Structure
(1998,
6,
839-848)
copyright 1998.