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Figure 4.
Figure 4. A close-up stereo view of the superposition of the structures of mutant gene V proteins (I47V, green; V35I,
magenta; V35I/I47V, cyan) on the structure of the wild-type protein (yellow lines). The mutant structures were first
aligned by least-squares superposition of the main-chain atoms on the wild-type. Only the relevant portions of the
structures are shown. The superposition of all mutants closely resemble that of the wild-type model as it is almost
impossible to distinguish color differences between the models except at the mutated site. Also, the two single mutants
in (a) closely resemble those of the double mutant in (b). For atom nomenclature see the legend to Figure 2. (a) V35I
and I47V versus WT; (b) V35I/I47V versus WT.
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