|
Figure 2.
Figure 2. Stereo views of Cα representations of individual
pertussis toxin subunits, in the same orientation as Figure 1a.
(a)S1, (b)S2, (c)S4, and (d)S5. S3, which is very similar to S2,
is not shown. The amino (N) and carboxyl (C) termini of each
subunit are labelled and the Cα atom of every tenth residue is
numbered. Secondary structure was assigned with DSSP [55]. S1 β
1, 6–11; α1, 15–21; β2, 23–24; α2, 32–37; β3,
50–54; α3, 57–77; β4, 83–92; β5, 97–99, α4,
100–111; α5, 118–127; β6, 129–133; β7, 135–136; β8,
141–150; β9, 155–162; β10, 191–193; β11, 198–199;
α6, 200–205; β12; 225–227; α7, 228–231. S2 and S3
amino-terminal domain: β 1, 27–29; α1, 32–37; α2,
39–48; β2, 54–56; β3, 61–63; β4, 70–72; β5, 84–93.
Carboxy-terminal domain: β6, 100–105; β7, 106–113; β8,
119–125; β9, 128–135; α3, 146–159; β10, 163–173;
β11, 183–191. S4: β1, 6–10; β2, 11–20; β3, 27–36;
β4, 48–55; α1, 63–74; β5, 78–89; β6, 92–102. S5:
β1, 5– 9; β2, 10–20; β3, 23–31; β4, 37–43; α1,
51– 66; β5, 70–74; β6, 84–91. Figure 2. Stereo views
of Cα representations of individual pertussis toxin subunits,
in the same orientation as Figure 1a. (a)S1, (b)S2, (c)S4, and
(d)S5. S3, which is very similar to S2, is not shown. The amino
(N) and carboxyl (C) termini of each subunit are labelled and
the Cα atom of every tenth residue is numbered. Secondary
structure was assigned with DSSP [[4]55]. S1 β 1, 6–11; α1,
15–21; β2, 23–24; α2, 32–37; β3, 50–54; α3, 57–77;
β4, 83–92; β5, 97–99, α4, 100–111; α5, 118–127; β6,
129–133; β7, 135–136; β8, 141–150; β9, 155–162; β10,
191–193; β11, 198–199; α6, 200–205; β12; 225–227;
α7, 228–231. S2 and S3 amino-terminal domain: β 1, 27–29;
α1, 32–37; α2, 39–48; β2, 54–56; β3, 61–63; β4,
70–72; β5, 84–93. Carboxy-terminal domain: β6, 100–105;
β7, 106–113; β8, 119–125; β9, 128–135; α3, 146–159;
β10, 163–173; β11, 183–191. S4: β1, 6–10; β2, 11–20;
β3, 27–36; β4, 48–55; α1, 63–74; β5, 78–89; β6,
92–102. S5: β1, 5– 9; β2, 10–20; β3, 23–31; β4,
37–43; α1, 51– 66; β5, 70–74; β6, 84–91.
|
