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Figure 2.
Crystal structures of MutT apo and MutT-8-oxo-dGMP complex
forms. A, overall structure of MutT. α-Helices are in pink, and
β-strands are in slate. A missing region of L-A is shown as a
gray dashed line. B, overall structure of MutT-8-oxo-dGMP.
8-Oxo-dGMP is shown in ball and stick representation. C,
comparison of the structures of the apo and complex forms. Apo
and complex forms are shown in gray and slate, respectively. L-A
and L-D regions in MutT-8-oxo-dGMP adopt a closed conformation
as compared with those in the apo form.
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