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Figure 2.
(a) Top, a dissociative transition state for E. coli with
ribooxacarbenium ion character^10. Bottom, structures of stable
analogs for an early dissociative transition state (ImmA) and a
late dissociative transition state (DADMe-ImmA) depict
differences in bond distances between the adenine leaving group
and the ribosyl group, as well as charge localization. TS,
transition state. (b) The structure of S-substituted DADMe-ImmA,
along with MT, EtT and BuT substituents.
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