Figure 2 - full size

 

Figure 2.
Fig. 2. Electron density at the active site for SaDHFR(F98Y):NADPH:5. Protein is shown with 2F[o]–F[c] density (1.5 σ, blue) and ligands are shown with omit F[o]–F[c] density (3.0 σ, grey). A full view of the density for the alternative conformation is shown at the right.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2009, 387, 1298-1308) copyright 2009.