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Figure 2.
Overall structure of LpxR. (A) Ribbon representation of LpxR.
The ribbon is colored with a gradient from the N terminus in
blue to the C terminus in red. Aromatic residues located at the
membrane boundaries are shown as cyan sticks. Membrane
boundaries are indicated by black lines. The extracellular side
is located at the top of the figure, and the periplasmic side is
at the bottom. Active-site residues are shown as yellow sticks.
Zn^2+ atoms are shown as gray spheres, and glycerol molecules
are shown as sticks in green. Loops, turns, the N terminus, and
the C terminus are labeled. (B) LpxR viewed from the periplasmic
side of the protein. The representation of the structure is
similar to that in A. Figs. 2, 3, 4, S2, and S5 were prepared
with PyMOL (23).
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