|
Figure 2.
Figure 2: Overall structure of the SRA–hemi-methylated CpG DNA
complex. a, Ribbon representation of the SRA–DNA complex in
the same orientations as in Fig. 1a: grey, SRA; orange, N-tail
and finger loop; light blue, loop L3; light green, DNA; magenta,
flipped-out base 5mC[7]. b, Schematic representation of the
protein–DNA interactions observed in the crystal structure.
Hydrogen bonds between SRA and DNA are shown by red lines:
dotted, main-chain contacts; solid, side-chain contacts. Van der
Waals contacts between SRA and DNA are shown by blue lines. W,
water molecules mediating indirect interactions.
|
