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Figure 2.
Fig. 2. Structure of IL-23. (a) Side view of the IL-23
crystal structure. p19 helices A to D are colored magenta, and
p40 domains 1 to 3 are colored blue. The single
N-acetylglucosamine residue attached to Asn200 on p40 is shown
in red. Disulfide linkages are colored yellow. (b) Face-on view
of IL-23. Receptor interaction sites 2 and 3 are highlighted in
ovals, and the key site 3-interacting side chain of Trp137 is
displayed.
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