Figure 2 - full size

 

Figure 2.
Figure 2. Superposition of antibody 9E10 C[ ]traces (variable domains) in stereo representation. (A) The epitope peptide complex for Fab(a) (V[L]: blue; V[H]: yellow; epitope peptide: red sticks) and Fab(b) (V[L]: light blue; V[H]: orange). Only the framework C[ ]coordinates were used for superposition, yielding an rmsd of 0.92 Å. (B) Fab(a) from the complex (light chain: blue; heavy chain fragment: yellow; epitope peptide: red sticks) and free Fab(a) (light chain: light blue; heavy chain fragment: orange, rmsd 0.45 Å for framework C[ ]positions).

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2008, 73, 552-565) copyright 2008.