Figure 2 - full size

Figure 2. Overlay of the backbone hinge region (residues 46 --57) of cyanovirin, monomer and dimer, and of P51G-m4-CVN. The monomeric NMR structure of wt CV-N (PDB code 2EZM) is represented in yellow, while the domain-swapped crystal structure (PDB code 1M5M) is represented in gray, and the monomeric crystal structure of P51G-m4-CVN in green (PDB code 2RDK; this work). Only the side chain of P51 (wt) is shown. In 2EZM, S52 assumes disallowed backbone dihedral angles.

The above figure is reprinted from an Open Access publication published by the Protein Society: Protein Sci (2008, 17, 939-944) copyright 2008.