Figure 2.
(a) IRK is shown as a molecular surface, with the N lobe
colored dark gray and the C lobe colored light gray. The
activation loop (residues 1150–1171) is colored green and the
catalytic loop (residues 1130–1137) is colored orange. IRS2
KRLB^Y628 is shown in stick representation. The final 2F[o] -
F[c] electron density (1.65-Å resolution, 1 contour)
is shown in blue mesh. The N and C termini of the peptide are
labeled.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Mol Biol
(2008,
15,
251-258)
copyright 2008.
contour)
is shown in blue mesh. The N and C termini of the peptide are
labeled.