Figure 2 - full size

 

Figure 2.
Figure 2. Structural comparison of human NPM-core decamer with other histone chaperones. (A) Comparison of human NPM-core decamer (colored in blue) and Xenopus NO38-core decamer (orange). Bottom pentamers are superimposed to display the rotational offset. Upper and lower right views are obtained by rotating the top and bottom pentamers by 90° around a horizontal axis, respectively. The views are from the center of the decamer and the viewing direction is slightly tilted from the fivefold axis to emphasize the structural difference. (B) Superposition of bottom pentamers of human NPM-core (colored in blue), Xenopus NO38-core (orange), and Xenopus nucleoplasmin-core (green). (C) Comparison of top pentamers of human NPM-core (colored in blue), Xenopus NO38-core (orange), and Xenopus nucleoplasmin-core (green) after superposition of the bottom pentamers.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2007, 69, 672-678) copyright 2007.