Figure 2 - full size

 

Figure 2.
Figure 2. Structural alignment of Exo70 in M. musculus, H. sapiens, D. melanogaster, S. pombe, and S. cerevisiae. Invariant residues are shaded purple. Similar but not identical residues are shaded pink. Secondary structural elements are indicated above the sequence block for MmExo70 and below for ScExo70: α-helices, rectangles; other elements, continuous lines; structurally unobserved residues, broken lines. For MmExo70: N domain, red; M domain, yellow; and C domain, blue (same as Figure 1). For ScExo70: N domain, brown; M domain, green; and C domain, cyan. For clarity, sequences lacking homology or unobserved in the structures have been replaced with bracketed numbers indicating the number of residues omitted.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2007, 371, 410-421) copyright 2007.