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Figure 2.
Fig. 2. Bisphosphonates and GGPPS structures. (A)
Structures of bisphosphonates investigated as GGPPS inhibitors.
(B) GGPPS structure containing zoledronate (PDB ID code 2E91)
showing dimer structure. (C) Stereoview of minodronate bound to
GGPPS (PDB ID code 2E92). (D) Stereoview of zoledronate/GGPPS
(PDB ID code 2E91) superimposed on zoledronate/IPP/FPPS
structure (PDB ID code 2F8C).
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