Figure 2 - full size

 

Figure 2.
FIGURE 2. Comparison of G336V PGDH with native PGDH. Left, comparison of L-serine binding to native PGDH ( ) and G336V PGDH ( ). The data are plotted as in Fig. 1. Right, comparison of the inhibition of enzymatic activity by L-serine in native PGDH ( ) and G336V PGDH ( ). The fractional inhibition of enzymatic activity (Inhibition) is plotted versus the total concentration of L-serine.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2007, 282, 18418-18426) copyright 2007.