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Figure 2.
Figure 2 Structure of Saccharomyces cerevisiae Rrp40  N.
(A) Crystal structure of S. cerevisiae Rrp40 N
(comprising residues 63–236). The S1 domain, the KH domain and
the conserved GxNG motif are indicated. (B) Superposition of the
structures of Rrp40 N
(magenta) and of AfRrp4 (orange; Büttner et al, 2005). The
two different GxxG sequence motifs present in AfRrp4 are
indicated. (C) Detailed view of the GxNG loop connecting  7
and 8
in the ScRrp40 KH domain. Hydrogen bonds formed by Asn 191
with residues of the S1 domain are indicated by dotted lines.
(D) View of the S1–KH domain interface. Conserved hydrophobic
side chains, which stabilize the domain interface, are shown in
black. Af, Archaeoglobus fulgidus.
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