Figure 2 - full size

 

Figure 2.
Figure 2: Structure and interactions in the TPP-binding pocket. a, Stereo view of the central region of the complex containing bound TPP. b, View of TPP, coordinated Mg^2+ ions (magenta) and water (blue spheres) in the binding pocket. c, Details of the interactions between the HMP ring and RNA. d, Hydrogen bonding between Mg^2+ ions and RNA.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nature (2006, 441, 1167-1171) copyright 2006.