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Figure 2.
Structural comparison of CA proteins. (A) Superposition of
the overall structures of S170A, S170C, E159Q, Y202L, R226K, and
the mature CA. Each structure is shown in yellow, cyan, dark
green, green, slate blue, and marine, respectively. To emphasize
the differences of the pro segments, the pro segment of Y202L is
shown in red. Residues Gly-160, Ser-170, Tyr-202, and Arg-226
are shown in a ball-and-stick representation in magenta. (B)
Stereoview of the pro-segment conformation of Y202L. The
electron density map corresponds to the 2 F [o] − F [c] map
calculated at 0.5 σ.
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