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Figure 2.
Figure 2 Overview of the solution structure of the RBD of Fox-1
in complex with UGCAUGU. (A) Overlay of the final 30 structures
superposed on the heavy atoms of the structured parts of the
protein and of the RNA. The protein backbone is gray, the RNA
backbone is orange, the phosphate groups are red, and the RNA
bases are yellow. Only the ordered region of the protein
(residues 116-194) is shown. (B) Surface (heavy atoms of
residues 116-194) and stick (heavy atoms of the RNA)
representation of the lowest energy structure. The protein
surface is painted according to surface potential with red
indicating negative charges and blue indicating positive
charges. The RNA is colored as in panel (A). (C) The lowest
energy structure in ribbon (protein backbone) and stick (RNA)
representation. The color scheme is the same as in (A),
important protein side chains involved in hydrophobic
interactions with the RNA are represented as green sticks. (D)
Same as (C) but rotated by 90° around the indicated axis.
Figures were generated with MOLMOL (Koradi et al, 1996).
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