|
Figure 2.
Fig. 2. Structure of the KvAP-33HI complex and comparison
with previous KvAP structures. (a) Stereo view of a single KvAP
subunit from the side with extracellular solution above. S1-S4
helices are colored blue. (b) Stereo view of a single KvAP
subunit of the KvAP-6E1 Fab complex (PDB ID code 1ORQ [PDB]
). (c) Comparison with the isolated voltage sensor structure.
Stereo view of a superposition of the isolated voltage sensor
(gold, PDB ID code 1ORS [PDB]
) and the KvAP-Fv complex (blue). The S2 helix (Leu-55 to
Tyr-75) was used for superposition, and the S1 helix is not
shown. Residues Asp-62, Asp-72, Arg-76, Glu-93, and Arg-133,
which are important for channel function, are shown in
ball-and-stick representation.
|
