Figure 2.
FIGURE 2. Relative distribution of the VBS peptides among
the 63 predicted -helices which make up
the talin rod. Vinculin binding helices are shown in blue and
non-binders in gray. VBS1-3 (peptides 4, 12, and 46) were
previously mapped using a yeast two-hybrid assay (21). The black
line indicates the position of an integrin binding site
(residues 1984-2113) (18), and the red line the C-terminal actin
binding site (residues 2295-2541) (19, 20).
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2005,
280,
37217-37224)
copyright 2005.
-helices which make up
the talin rod. Vinculin binding helices are shown in blue and
non-binders in gray. VBS1-3 (peptides 4, 12, and 46) were
previously mapped using a yeast two-hybrid assay (21). The black
line indicates the position of an integrin binding site
(residues 1984-2113) (18), and the red line the C-terminal actin
binding site (residues 2295-2541) (19, 20).