Figure 2.
Figure 2. (A) The TM1464 trimer viewed along the 3-fold axis.
One subunit is shown in blue. The 3 UNLs bound to the putative
active sites are shown as red spheres. (B) TM1464 shown in
surface representation illustrating the narrow active site
pocket, with the bound UNL in ball-and-stick configuration. (C)
Close-up of the putative active site. TM1464 is shown in ribbon
representation with the UNL, manganese, and interacting residues
and waters in ball-and-stick configuration (see text). A
SigmaA-weighted Fo-Fc omit map contoured at 3.0 is
shown for the UNL, manganese, and coordinating waters. Putative
H-bond interactions between the UNL and the protein are shown in
yellow dotted lines.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2005,
59,
864-868)
copyright 2005.
is
shown for the UNL, manganese, and coordinating waters. Putative
H-bond interactions between the UNL and the protein are shown in
yellow dotted lines.