Figure 2.
Figure 2. Comparison of the current NMR structure of
monomeric SDF-1a (red, labeled as NMR(1VMC)), with (a) the
coordinates of one subunit from two independent crystal
structures of dimeric SDF-1a solved at resolutions of 2.2
Å (blue, 1A15)9 and 2.0 Å (green, 1AQG7),10 and (b)
the original monomeric NMR structure (gray, 1SDF) solved by
Crump et al.4 Note that the orientation of the helix with regard
to the underlying b-sheet in the 1SDF structure differs by vert,
similar 35° from that in the other three structures, and the
conformation of the loop connecting strand b3 to the helix is
significantly different as well.
The above figure is reprinted
by permission from Elsevier:
J Mol Biol
(2005,
345,
651-658)
copyright 2005.
vert,
similar 35° from that in the other three structures, and the
conformation of the loop connecting strand b3 to the helix is
significantly different as well.