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Figure 2.
Figure 2. Details of the PY-binding site within the ribosome.
(a) Stereo view of the location of critical 16S rRNA residues
G926, C1400, C1402 and A1493 (green) relative to PY. Helix 69
(H69) of 23S rRNA is blue. Conserved residues within PY are
magenta^3. (b) Overlap of PY with A- and P-site tRNAs. A-, P-
and E-site tRNAs are cyan, green and gray, respectively. The
positions of the 30S and 50S subunits, the path of mRNA, and the
location of the C-terminal tail of PY are indicated. (c) Overlap
of the difference electron density corresponding to PY with mRNA
(red). The positive density, E-, A- and P-site tRNAs are
color-coded as above. The negative density is not shown for
clarity. The 5' and 3' ends of the mRNA are marked.
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