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Figure 2.
FIG. 2. Multiple conformational states of Trp-102 in PETN
reductase. Panel A, stereo pair of the electron density of
Trp-102, picrate, and FMN observed at 1.55 Å, showing the
apparent formation of a bond between the nitro group of picrate
and the indole of Trp-102. The 6-membered ring appears to have
puckered, consistent with the loss of aromatic character. Panel
B, same view of electron density observed at 0.9 Å,
showing that the side chain of Trp-102 adopts two conformations,
each with partial occupancy, thus avoiding a steric clash with
the partially occupied picrate.
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