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Figure 2.
Figure 2. Structural arrangements, 2F[o]-F[c] (cyan)
electron density maps and Fourier difference maps (Fo-F[c]) at
+4  (green) and
-4 (red) of the
active site of AST (A-D) and BT (E-H). The inhibitors are (A)
benzamidine AST-1BZA, (B) benzylamine AST-2BEA, (C)
phenylethylamine AST-3PEA, (D) phenylpropylamine AST-4PPA, (E)
aniline BT-ANL, (F) benzylamine BT-2BEA, (G) phenylethylamine
BT-3PEA, and (H) phenylbutylamine BT-5PBA. Ser 190 is not
covered by electron density and only selected hydrogen bonds are
included to simplify the figure created by BobScript (Esnouf
1997). The sigma levels of the 2F[o]-F[c] maps are 1.1-1.5 (AST)
and 1.5-1.7 (BT).
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