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Figure 2.
FIG. 2. PRL phosphatases are highly homologous within their
family but show low sequence similarity to the catalytic domains
of other dual specificity phosphatases. The aligned phosphatases
include human PRL-3 (gi:14589856), PRL-1 (gi:4506283), PRL-2
(gi:4506285), Drosophila PRL-1 (gi:3135665), worm PaRaLysed_cae
(gi:17569857), human VHR (gi:181840), CDC14 (gi:34811075), PTEN
(gi:1916328), and KAP (gi:443669). The secondary structural
elements refer to PRL-3. The catalytic residues are shown in
bold type.
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