Figure 2.
FIG. 2. The least squares superimposed structures of
wild-type human Mn-SOD (purple) and Y166F Mn-SOD (green) showing
residues in the active site. In the mutant, the side chain of
Asn171(B) emanating from the adjacent residue has rotated
130° around the C- -C- bond to form a hydrogen
bond with His30. The side chain of His30 has also rotated
98° around the C- -C- bond overlapping the
site of a water molecule in the wild type.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
5861-5866)
copyright 2004.
-C- 
bond to form a hydrogen
bond with His30. The side chain of His30 has also rotated
98° around the C-