Figure 2.
FIG. 2. Peptide electron density and differential
conformations in the HLA-B27 binding groove. A, electron density
map for the s10R peptide (F[o] - F[c] omit map, contoured at 3
,
for the final model with the peptide omitted from map
calculation). Superimposition of peptide binding grooves of
HLA-B27 protein complexes in the top (B) and side view (C)
orientation, with the C backbone conformation
for s10R (red), m9 (blue, from B^*2709·m9, PDB entry 1k5n
[PDB]
; cyan, from B^*2705·m9, PDB entry 1jge [PDB]
), and ARA[7] (yellow, B^*2705·ARA[7], PDB entry 1hsa [PDB]
), illustrating the stronger bulging of s10R out of the binding
groove. In C, helix 2 is omitted for
clarity.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2004,
279,
652-663)
copyright 2004.
,
for the final model with the peptide omitted from map
calculation). Superimposition of peptide binding grooves of
HLA-B27 protein complexes in the top (B) and side view (C)
orientation, with the C 
backbone conformation
for s10R (red), m9 (blue, from B^*2709·m9, PDB entry 1k5n