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Figure 2.
Figure 2. Structural Topology of the LIF/gp130 D2D3 Crystal
Structure(A) Backbone structure as viewed from the side of the
LIF/gp130 complex.(B) Close-up view of the interface showing
four clear spheres of electron density (green) calculated at 2.5
σ from an omit map representing buried solvent molecules.(C)
“Top” view of the LIF/gp130 complex showing LIF bound to
gp130 through its N-terminal region and the N-terminal flap.(D)
Close-up view of omit map electron density contoured at 2.5 σ
showing the well-ordered N-terminal flap. Molscript (Kraulis,
1991) and Raster3D (Merritt and Murphy, 1994) were used to
prepare secondary structure figures and Bobscript (Esnouf, 1997)
was used to prepare electron density figures.
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