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Figure 2.
FIG. 2. Interactions between NECA and GRP94. A, schematic
drawing showing the interactions. Hydrogen bonds are shown as
dashed lines, and van der Waals contacts are represented by
complementary double semi-circles. Red circles are water
molecules. Amino acid side chains are represented by ovals, and
backbone atoms are shown as squares. B, stereo view of the
GRP94·NECA interaction. Selected van der Waals surfaces
are depicted by dots, hydrogen bonds are depicted by dashed
lines, and water molecules are shown as green spheres. Oxygen
atoms are colored red, nitrogen blue, and carbon black. C,
stereo view of the binding of ADP in yeast Hsp90. The
coordinates were taken from PDB code 1AMW [PDB]
(15). B and C were prepared with Ribbons (47).
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