Figure 2 - full size

 

Figure 2.
Fig. 2. The internal hydrophilic cavity of LacY. The surface model and electrostatic potential were calculated with the program GRASP (38). The polar surfaces are colored blue (positively charged) and red (negatively charged). The black spheres denote TDG. (A) View parallel to the membrane. For clarity, helices V and VIII have been removed. (B) View along the membrane normal from the cytoplasmic side.

The above figure is reprinted by permission from the AAAs: Science (2003, 301, 610-615) copyright 2003.