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Figure 2.
Figure 2 Comparison of the variable domains of non-complexed
Fab-1696 (PDB code [59]1cl7 , blue), molecule 1 of the
non-complexed scFv-1696 (this work, yellow) and complexed
scFv-1696 (PDB code [60]1jp5 , red). The peptide is shown in
green. Superposition has been made by optimizing the
correspondence between the main-chain atoms of the V[L] domains
of the three structures. Fv1696 is shown from the side of (a)
and from above (b) the antigen-bindng site. The V[L] domain is
shown on the left of the Fv fragment, while the V[H] domain is
on the right. The third CDR of V[H] (H3) is indicated.
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