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Figure 4.
Figure 4. Lactose Binding to TcTS(A) Complete BIAcore
sensorgrams showing the interaction between the inactive mutant
Asp59Asn and sialic acid (continuous line). Lactose (10 mM) was
injected after equilibrating the protein in the presence
(continuous line) or absence (dashed line) of sialic acid.(b)
Detailed view of the interaction between TcTS and lactose,
demonstrating that the acceptor substrate only binds to TcTS
when sialic acid is present.
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