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Figure 2.
Figure 2. Structural comparison of START domains. Stereo view
superposition of the C traces
of PC-TP (blue) and MLN64 (gray) based on 126 paired C positions.
The most similar regions are the -strands
of the central -sheet
that form the floor of the lipid binding tunnel, whereas the
most significant differences include the positioning of loop
1
and the C-terminal helix.
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