Figure 2 - full size

 

Figure 2.
Figure 2. Structural comparison of START domains. Stereo view superposition of the C traces of PC-TP (blue) and MLN64 (gray) based on 126 paired C positions. The most similar regions are the -strands of the central -sheet that form the floor of the lipid binding tunnel, whereas the most significant differences include the positioning of loop 1 and the C-terminal helix.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Biol (2002, 9, 507-511) copyright 2002.