Figure 2 - full size

Figure 2. Fig. 2. (A) Backbone (N,C^ ,C') superposition of 10 low-energy NMR-derived structures for viral KSHV Bcl-2. Helices are numbered with respect to those observed in the structure of Bcl-x[L]. (B) Ribbon (36) depiction of the average-minimized structure for viral KSHV Bcl-2. The central helix, 5, is colored yellow. (C) Solvent-accessible surface showing hydrophobic groove for viral KSHV Bcl-2. Leucine, isoleucine, valine, methionine, tyrosine, phenylalanine, and tryptophan residues are colored yellow. Aspartate and glutamate are colored red. Lysine, arginine, and histidine are colored blue. All other residue types are colored gray.