Figure 2 - full size

 

Figure 2.
Fig. 2. Structures of native and monosaccharide-bound MBP-A. The view is the same as that shown in Fig. 1A. For clarity, His189 and Ile^207 are shown only if they form contacts with the bound ligand. A, native crystal cryopreserved in MPD, showing the two water molecules that form the seventh and eighth coordination bonds with the Ca 2+. B, MeMan. C, MeGlcNAc protomer A (orientation I). van der Waals contacts between C6 of the pyranose ring and Ile^207 are shown. D, MeGlcNAc protomer C (orientation II). van der Waals contacts between the acetamido-moiety and Ile^207 are shown. E, MeFuc. van der Waals contacts between the side chain of His189 and the anomeric oxygen are shown. F, MeFuc.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2002, 277, 16088-16095) copyright 2002.