Figure 2 - full size

 

Figure 2.
Figure 2. Binding of HME in the active site of the D53,54N mutant of HDC. Residues from the right-hand monomer of the molecular interface are labeled with ( ). The pyruvoyl moiety (PVL) is part of the left-hand monomer and is shown bonded to HME. Hydrogen bonds are drawn with dashed lines.

The above figure is reprinted by permission from John Wiley & Sons, Inc.: Proteins (2002, 46, 321-329) copyright 2002.