Figure 2 - full size

 

Figure 2.
Figure 2. Fourier Difference Maps of mRNAs(A) 7 Å Fourier difference map of MK27 mRNA with the mRNA model (yellow) docked, showing the position of the Shine-Dalgarno (S/D) helix (magenta) and the positions of the A- and P-site codons (orange and red, respectively), viewed from the top of the 30S ribosomal subunit.(B) Difference map of the MF36 mRNA, showing a four-base-pair tetraloop helix (A-site helix) fitted to the extra density at the A site.(C) Same as for (B), except that the A-tRNA anticodon stem-loop (green) is shown in the position observed experimentally in the A-tRNA difference map (Yusupov et al., 2001), in place of the A-site mRNA helix. The five-nucleotide (GGAGG/CCUCC) core of the Shine-Dalgarno interaction is shown in magenta, and the rest of the 16S rRNA tail in cyan

The above figure is reprinted by permission from Cell Press: Cell (2001, 106, 233-241) copyright 2001.