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Figure 2.
Fig. 2. Complex of the 30S subunit with mRNA from a U[6]
hexanucleotide and a cognate tRNA-ASL. (A) Overview of the
complex. The 50S interface side of the 30S subunit is facing the
reader, and important elements have been given standard colors
that are used throughout the figures, namely, ASL at the A site
(gold), codon from the U[6] hexanucleotide at the A site
(purple), 3' end of 16S RNA that mimics mRNA at the P site
(green), P site tRNA mimic introduced by helix 6 from a
neighboring molecule (dark blue), and protein S12 (tan). (B)
Stereo view showing details of the A and P sites, colored as in
(A), with, in addition, helix 44 (cyan, right), helix 34 (blue,
left), 530 loop (green, left), and paromomycin (yellow sticks,
within helix 44). The hydrogen bonds responsible for the
codon-anticodon interaction at both the A and P sites are shown
as red lines.
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