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Figure 2.
Fig. 2. Coordination in the principal Ca^2+ site of
QPDWG-HDRPY. Carbon, nitrogen, oxygen, and calcium are
represented as white, blue, red, and green spheres,
respectively. Hydrogen bonds are shown as dashed black lines,
and Ca^2+ coordination bonds are solid green lines. a, GalNAc
complex, copy A. b, native, copy A. c, native, copy C. The two
alternate conformations of Asn210 are shown. d, native, copy B.
e, stereo view of superimposed copy A of the GalNAc complex
(white bonds) and native copy B (yellow bonds). f, schematic
drawing of the 8-coordinate Ca^2+ site in native copy A. g,
schematic drawing of the rearranged, 7-coordinate Ca^2+ site in
native copy B. The diagrams in f and g are in approximately the
same orientation shown in b and d, respectively, and emphasize
the rotation of the pentagonal equatorial coordination plane.
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