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Figure 2.
Figure 2 The three-dimensional structure of fumarate
reductase. a, The fumarate reductase dimer viewed parallel to
the membrane. The polypeptide backbones of the two A subunits
are shown in blue and light blue, those of the two B subunits in
red and pink, and those of the C subunits in green and yellow.
Subunit A contains a covalently bound FAD. Subunit B contains
three iron-sulphur clusters (Fe[2]S[2], Fe[4]S[4] and
Fe[3]S[4]). The membrane-embedded subunit C contains two haem b
molecules. b, View of the transmembrane helices of the subunit C
dimer along the membrane normal from the cytoplasmic side. One
monomer is colour-coded from blue (N terminus) to yellow (C
terminus), the other from yellow (N terminus) to red (C
terminus)). The transmembrane helices are labelled I, II, IV, V
and VI (ref. 22). Secondary structures were assigned using
DSSP49. Figure rendered with Raster3D^50.
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