Figure 2.
Figure 2. The S1' pockets of collagenases-1 and -3. a,
Collagense-3 with RS-130830 bound. b, Collagenase-1 with a
peptide-based inhibitor (PDB^26, ^27 accession code 2TCL^15). c,
Collagenase-1 in a complex with RS-104966. The S1' pockets are
represented by a solid surface representation of the enzyme. The
S1'-specificity loop is shown by a ribbon, and specificity
residue is identified.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(1999,
6,
217-221)
copyright 1999.
