Figure 12.
Figure 12. Alignment of inhibitors 2 (white) and 3
(orange). Human a-thrombin is shown by its solvent
accessible surface. The inhibitors were superimposed
using the atoms of amino acid residues His57, Asp102,
Asp189 and Ser195 of trypsin or thrombin, respectively.
Arrows indicate the location of the carboxylic groups.
The above figure is reprinted
by permission from Elsevier:
J Mol Biol
(2001,
313,
593-614)
copyright 2001.
